Instrumental Variables and confounder in Mendelian Randomization

Question

[Shicheng Guo]

I think the assumption about the relationship between instrumental variables and confounder in Mendelian Randomization is not clearly explained. anyone can share the details requirement for the relationship between IV and confounder? Thanks.

Answer 1

[Amy Mason]

Try this presentation: https://caleb-huo.github.io/teaching/2020SPRING/lectures/MR.pdf - particularly slides 11 & 12