Wikipathways, Reactome, and Pathway Commons all contain pathway information which is supported in BioPAX 3.0.
All three publish BioPAX representations of their data.
Wikipathways and Pathway Commons allow access to a 'release' of their respective representations via HTTP server which can accept and process BioPAX-compatible graph patterns written SPARQL
EMBL hosts a separate representation of the Reactome BioPAX representation.
I'm just learning about these but somehow it seems that Pathway Commons is a meta-resource, which includes Reactome, etc.
My questions are:
1) does the Pathway Commons BioPAX merge the graphs of all its constituent databases (including Reactome, etc.), such that the Reactome RDF is 100% redundant given Pathway Commons RDF?
2) if so then should I always just query Pathway Commons (i.e. no need for federated queries)?