Convert variant coordinates from one genome build to the other
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4.2 years ago
Gene_MMP8 ▴ 240

I have a list of variants (Chromosome/Position/Ref/Alt) based on the GrCh38 build of the human genome. To reproduce the results from a paper, I have to map these coordinates to the GrCh37 build of the human genome. Now I understand that the UCSC LiftOver tool maps the coordinates (Chrosome/Position) of the given set of variants from one build to the other. But how do I map the corresponding Reference/Alternate alleles to the GrCh37 build? Is there any tool that does that?

sequence variant genome_build • 1.3k views
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Thanks for sharing. Much appreciated. Just to clarify I will get the reference/alternate allele mapping too, right?

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I will get the reference/alternate allele mapping too, right?

yes

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