How to check if baseline methylation levels influence response to intervention?

Question

[macsuejacques]

Hello,

I have DNA methylation data from EPIC arrays, for baseline, post 4W, post 8W and post 12W. I would like to check if baseline methylation levels had any influence in the response to the intervention. For example if a participant that had more methylation levels at baseline was the one to present the highest changes overtime or vice versa. It doesn't matter if I do this based on whole methylome levels or by genes for example. I just would like to know if there is a way to check this and how would the model be?

Thank you in advance.