compare expression for 1 gene between more than 2 samples

Question

[Sara]

what is the best way to compare expression for 1 gene between > 2 samples? FPKM/RPKM/TPM/CPM or log2 FC

Answer 1

[noahhelton98]

If you used the same control for each of the different samples, then any measure should be fine. Differential gene expression is relative, so when comparing expressing across multiple samples you can compare their relative change to the control and use that when talking about the data. Log2FC should be adequate, but wording is key.