Random Boolean network with same input nodes as original network
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Entering edit mode
4.1 years ago
priya.bmg ▴ 60

Hi,

I have a Boolean network as given below this question. How do I create a random Boolean network with the same input nodes as the original network?. Is there way to randomly change the logic gates? Has anyone tried to create random Boolean network with same input nodes as your original network but the rules or connections between them changed in a systematic manner? Thanks

Gene1 = not(IG5 or IG6) and (Gene2 and IG2) and (IG9)
Gene2 = not(IG6 or Gene1) and (IG5 and IG9) 
Gene3 = not (IG5 or IG7) and (Gene1 and IG2) and (IG3 or IG4) 
IG1 = IG2 and IG9
IG2 = IG4
IG5 = IG1
IG3 = not(IG6)
IG4 = not(IG5 or IG6)
IG5 = IG4 
IG6 = IG9
IG7 =IG3
IG9 = not(IG5)

Priya

random Boolen network Genetic regulatory network • 629 views
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Entering edit mode
4.1 years ago

Look at the BoolNet R package and its generateRandomNKNetwork() function which can be configured in different ways.

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