P-value adjustment for diffreent classes each tested individually

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4.0 years ago

english.server ▴ 300

Hi there!

Testing the effect of a certain gene on survival of GBM and LGG patients, with each cancer (GBM or LGG) having several subtypes, how should I adjust for multiple testing? Especially that survival analysis consists of disease-free and overal survival. Should I adjust for all measurements or can I consider GBM/LGG separately or overall survival/disaase-free-survival separatey (so that I get a significant adjusted p-value? )

update: I (cross)posted the question: https://stats.stackexchange.com/questions/495509/p-value-adjustment-for-different-classes-each-tested-individually

survival p-value adjustment • 1.1k views

ADD COMMENT • link 4.0 years ago by english.server ▴ 300

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More suited to Cross Validated, I think: https://stats.stackexchange.com/

ADD REPLY • link 4.0 years ago by Kevin Blighe 88k

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Thank you Dr Blighe. I posted to Cross Validated and updated my question to include the fact.

ADD REPLY • link 4.0 years ago by english.server ▴ 300

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