how to select important / meaningful mutation sites of SARS-CoV-2 ?
1
0
Entering edit mode
4.1 years ago
2001linana ▴ 40

I'd like to do a research concerning SARS-CoV-2 mutations. I was wondering, how to select important / meaningful mutations or do I need to analyse / compute mutations by sequences alignment, trimming, and computer analysis softwares? Any comments are greatly appreciated.

RNA-Seq sequencing • 1.0k views
ADD COMMENT
0
Entering edit mode

The question is too vaguely formulated e.g. mutations important for what? For how to deal with sequence variations, take a look at existing workflows, for example on the Galaxy COVID 19 portal.

ADD REPLY
0
Entering edit mode

2001linana : Don't forget to follow up on your threads.

If an answer was helpful, you should upvote it; if the answer resolved your question, you should mark it as accepted. You can accept more than one if they work.
Upvote|Bookmark|Accept

ADD REPLY
1
Entering edit mode
4.1 years ago
yjn ▴ 20

Maybe you can have a look at GenBrowser(http://www.egps-software.org/ )which provides convenience for analysis of nCOV-19 data. The main functions include evolution tree visualization, genome browser and related data analysis. And our next version will soon pop up online which provides non-neutral evolution analysis function in Stand-alone version.

ADD COMMENT
0
Entering edit mode

can not find this software.

ADD REPLY
1
Entering edit mode

Try now. Link corrected above.

2001linana : You have asked a lot of questions here in past few days. That is great but you should follow-up on past threads by validating comments/answers. Participants are all volunteering their time and acknowledging their help is perfect way of showing your appreciation for that help.

ADD REPLY
0
Entering edit mode

http://www.egps-software.org/,you can download the software in this website.

ADD REPLY

Login before adding your answer.

Traffic: 1644 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6