downloading of datasets for construction of a model pathway

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4.0 years ago

ravi.eshwari ▴ 10

Hi members,

My friend has been assigned a task to model a pathway of IL6/II6R/gp30 using systems biology approach. However she needs help as to how to download the tissue expression datasets of each of these genes and what type of dataset should she be using for the same. Kindly help!!

Thanks Much for your time!

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ADD COMMENT • link updated 21 months ago by Ram 44k • written 4.0 years ago by ravi.eshwari ▴ 10

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What exactly does "model a pathway" mean? Isn't this something that you can lookup in resources like the REACTOME pathway viewer?

ADD REPLY • link 4.0 years ago by ATpoint 85k

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He is probably talking about genome scale metabolic network since that is the systems biology approach for reconstruction/modelling of pathways. You would need a lot more than just expression datasets to achieve that.

ADD REPLY • link 4.0 years ago by ashish ▴ 680

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construct a pathway of IL6 using systems biology approach

I am sorry about wrong terminologies used if any since I am not aware of systems biology subject

ADD REPLY • link 4.0 years ago by ravi.eshwari ▴ 10

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