Mapping reads to circular references
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3.9 years ago
wes ▴ 90

Is there any program can be used to map subreads (from pacbio) against circular references (plastome)? Previously, I tried to use minimap to map against the reference. However, there is a drop in coverage at both ends of the reference.

alignment • 1.3k views
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Can't you just pad the end of the reference with sequence from the beginning?

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