How to map Affymetrix IDs to Gene Symbols using hgu133a.db R package?

Question

[prithvi.mastermind]

if (!requireNamespace("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("hgu133a.db")
library(hgu133a.db)
VB <- read.table(file = "PROBE.txt")
x <- hgu133aSYMBOL(VB)


MY Input Data:


218865_at
219574_at
210075_at
219527_at
221636_s_at
213256_at
218582_at
201736_s_at
201737_s_at
212498_at
215422_at
215423_at

Answer 1

[Kevin Blighe]

library(hgu133a.db)

probes <- c('218865_at','219574_at','210075_at','219527_at','221636_s_at',
  '213256_at','218582_at','201736_s_at','201737_s_at','212498_at','215422_at',
  '215423_at')

annotLookup <- select(hgu133a.db, keys = probes,
  columns = c('PROBEID', 'ENSEMBL', 'SYMBOL'))

annotLookup
       PROBEID         ENSEMBL  SYMBOL
1    218865_at ENSG00000186205   MARC1
2    219574_at ENSG00000145416 MARCHF1
3    210075_at ENSG00000099785 MARCHF2
4    219527_at ENSG00000117791   MARC2
5  221636_s_at ENSG00000117791   MARC2
6    213256_at ENSG00000173926 MARCHF3
7    218582_at ENSG00000198060 MARCHF5
8  201736_s_at ENSG00000145495 MARCHF6
9  201737_s_at ENSG00000145495 MARCHF6
10   212498_at ENSG00000145495 MARCHF6
11   215422_at ENSG00000145495 MARCHF6
12   215423_at ENSG00000145495 MARCHF6

[fahim]

If the probe id list is huge than how can be retrieved them??