Better place to download dbSNP than official ftp site?
1
0
Entering edit mode
3.9 years ago
MatthewP ★ 1.4k

I need to download dbSNP of VCF format. If I download the last release b154 from
https://ftp.ncbi.nih.gov/snp/latest_release/VCF/GCF_000001405.38.gz
The problem is the contig name is not chromosome, but something like "NC_000001.11", "NT_113793.3", "NW_019805489.1".

If I dowload older version b151 from
https://ftp.ncbi.nih.gov/snp/organisms/human_9606_b151_GRCh38p7/VCF/All_20180418.vcf.gz
The problem is no contig in header, I added by hand for example ##contig=<ID=1>. But there is one value MTP in INFO field with no definition in header. Does anyone know the definition so I can add to header.

dbSNP • 3.1k views
ADD COMMENT
2
Entering edit mode
3.9 years ago

The problem is the contig name is not chromosome, but something like "NC_000001.11"

rename the chromosomes with bcftools annotate. This file will help to get the two-columns file: https://ftp.ncbi.nlm.nih.gov/genomes/all/GCF/000/001/405/GCF_000001405.39_GRCh38.p13/GCF_000001405.39_GRCh38.p13_assembly_report.txt

ADD COMMENT

Login before adding your answer.

Traffic: 1840 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6