I have a set of DE HGNC_Symbols which I wanted to map onto the equivalent protein_ids. I've used the mygene package to do this setting the species to human.
All_DE_Proteins <- queryMany(v6$HGNC_Symbol, scopes="symbol", fields=c("name", "uniprot", "ensembl.gene"), species="human", as_dataframe=True)
I was wondering what the code would be to set the species to cricetulus griseus, ie Chinese hamster, as the cells I work with are CHO cells.
I was also wondering does the species choice really matter, if the gene names are the same across both CHO and human? I haven't looked at the sequence homology of the 1000 plus DE genes in my dataset across the two species but some of my genes don't return any results, for example, "AARS" which according to https://genecards.weizmann.ac.il/v3/cgi-bin/carddisp.pl?gene=AARS is an Alanyl-TRNA Synthetase with the SwissProt ID P49588, so I would have expected a result.
