Question

Why there is no beta of SE output in some meta GWAS results?

0

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5.7 years ago

lilingjoyo ▴ 40

Hi all,

I want to use a summary statistics of a meta GWAS result. The meta analysis was performed by using META. In the summary statistic table, there are z-score and p-value columns, but no beta or SE columns. But I need beta as my input. Here is header of the summary table

SNP CHR BP  Allele1 Allele2 N   Zscore  P

I know that the conversion between beta and zscore is that:

zscore = beta / SE

How could I calculate beta based on provided info?

gwas meta beta SE • 3.5k views

ADD COMMENT • link updated 3.8 years ago by DM ▴ 40 • written 5.7 years ago by lilingjoyo ▴ 40

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Do you mean METAL software?

ADD REPLY • link 5.7 years ago by zx8754 12k

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Sorry, spelling mistake. Yeah, it's METAL.

ADD REPLY • link 5.7 years ago by lilingjoyo ▴ 40

score 1 · Answer 1 · 2021-02-01

1

Entering edit mode

3.8 years ago

DM ▴ 40