Vcf file to vcf.gz

Question

[shiwali-goyal]

Dear All,

I have vcf file with me and I want to convert this vcf file to vcf.gz format. Please help me regarding this. I am not aware of scripts so it would be good if anyone can tell me the stepwise procedure to convert my vcf file to vcf.gz type. Thanks in advance!

Regards
Shiwali

Answer 1

[Pierre Lindenbaum]

htslib: https://github.com/samtools/htslib

bgzip file.vcf

bcftools: https://github.com/samtools/bcftools

bcftools view -O z -o file.vcf.gz file.vcf