What test can be conducted to check ratio between the groups are significant ?

Question

[DareDevil]

I have a table containing following information:

Group       High    Low      No     Pos
T.CD8       0.11    0.06    0.07    0.09
T.CD4       0.01    0.01    0.01    0.01
T.reg       0.02    0.01    0.02    0.02
Macro.M0    0.09    0.14    0.15    0.11
Macro.M1    0.17    0.10    0.07    0.14
Macro.M2    0.07    0.14    0.11    0.10

I am trying to find ratio between two Groups Macro.M1 / Macro.M2 in High, Low, No and Pos groups

I got the ratio as follows:

High    Low      No     Pos
2.49    0.76    0.62    1.43

How can I derive a p-value for this test meaning High has significant difference from other group ratio?

[Jean-Karim Heriche]

To compute p-values, you need a distribution.

[ATpoint]

Can you add some details what these data are? I see cibersort so this is probably something related to deconvolution? Can you give some details?