Getting matched peptide to CDR3 sequences

Question

[zizigolu]

Hi

I have CDR3 sequences of a patient like below

CASSYLPGQGDHYSNQPQHF
CASSFEAGQGFFSNQPQHF
CASSFEPGQGFYSNQPQHF
CASSYEPGQVSHYSNQPQHF
CASSALASLNEQFF
CASSYLPGQGDHYSNQPQHF
CASSFEAGQGFFSNQPQHF
CASSFEPGQGFYSNQPQHF
CASSYEPGQVSHYSNQPQHF
CASSYLPGQGDHYSNQPQHF
CASSFEAGQGFFSNQPQHF
CASSFEPGQGFYSNQPQHF
CASSYEPGQVSHYSNQPQHF
CASSYLPGQGDHYSNQPQHF
CASSFEAGQGFFSNQPQHF
CASSFEPGQGFYSNQPQHF
CASSYEPGQVSHYSNQPQHF
CASSFGVEDEQYF

How I can find their matched epitope/peptide? Lets say FLKEKGGL which is attached to CASSYLPGQGDHYSNQPQHF

[GenoMax]

Can you clarify the context? What is CDR3 and what matched epitope are you referring to?

[zizigolu]

The CDR3 region is the preferential target of many T cell receptor (TCR) repertoire studies, due to its relevance for TCR-peptide interaction

I have amino acid sequence of CDR3 and I want to they would attached to which epitope/peptide (antigen)

[Joe]

This is not really my area of expertise, so I'll bow out to others more qualified, but based on experience with MHC peptide presentation etc., as far as I know these types of interaction are not well understood and even harder to predict.

I wouldn't be surprised if there is not an answer to this question (certainly not an easy one).