What is KEGG BRITE ?

Question

[fyfes]

Hi, I am downloading some pathways for bacteria from KEGG using Bioservices Python package and sometimes I get ko01057 which can be assigned to KEGG class and sometimes map07021 which cannot be assigned to CLASS and is BRITE hierarchy. What is the difference? thank you

[khemlalnirmalkar]

Hi, @fyfes, Did you get the answer to your questions? If yes, please can you share it here with me?

Thanks Khem

Answer 1

[MatthewP]

KEGG contains 18 databases in four categories. KEGG BRITE is one of them, the most wellknow one is KEGG PATHWAY. You can get information of BRITE database from KEGG website, click KEGG BRITE and you can see overview of BRITE database:

KEGG BRITE is a collection of hierarchical classification systems capturing functional hierarchies of various biological objects, especially those represented as KEGG objects. They are represented as BRITE hierarchy files, also called hierarchical text (htext) files, supplemented with BRITE table files using html tables. BRITE hierarchy files may contain tab-delimited attributes that are added manually or computationally. BRITE table files focus more on such multi-column attributes rather than hierarchy relationships. In contrast to KEGG PATHWAY, which is limited to molecular interactions and reactions, KEGG BRITE incorporates many different types of relationships including: 1. Genes and Proteins 2. Compounds and Reactions 3. Drugs 4. Diseases 5. Organisms and Cells

KEGG BRITE is the reference database for brite mapping in KEGG Mapper.

I would suggest you to investigate KEGG website and their paper: KEGG: integrating viruses and cellular organisms