I have carried out RNA-Seq for lncRNAs. I have 8 lncRNAs that are differentially expressed and all 8 overlap CTCF binding sites when viewed in Ensembl genome browser. How do I go about proving that this is statistically significant and not happening by chance? I have read in papers where they have done something similar but they never state how they did it. Also could someone tell me where I actually find out exactly how many CTCF binding sites there are? (for human) . I cannot find this information from Ensembl. Many thanks.