Hi: I have a set of gene signatures obtained by SAM that contains data like this:
Gene ID Score (sd)
123456_at 45,5655
....... ........
where Score is the t-statistics obtained.
The question that I have is based on that data, how I can obtain the enrichment score using bioconductor?
Hi Marco Aurelio. Enrichment score of what? Do you mean GO term enrichment analysis? KEGG pathway enrichment analysis? Do you just want the p-value of your score? Try to be a bit more specific, and it will be easier to help you.
I want to compare this list of genes with a data matrix that contains a set of probe sets ordered by their differential expression between healthy and disease samples.
If I have the set of up and down regulated genes as a signature from SAM, how can I compute an enrichment score for these genes, if I have only the t-statistics? thanks