Database Of Cell Types, Division Rates, And Differentiation

Question

[hbw]

Does anyone know of sources for a large variety of cell types, their division rates, and differentiation for humans. I am not looking for publications looking at one or two types of cell types, but I want to compare a number of systems (say skin, liver, lung, etc) as to the types of stem cells present, how frequently they divide at each step and die all the way to the major different types of cells in the system. Is there any such database/survey out there?

Answer 1

[Mary]

I am in the middle of watching the #vcell workshop today and one of the talks just went into a project where they are modeling a virtual embryo. They might have that type of data or links to where they are getting theirs. Might look around their site: http://www.epa.gov/ncct/v-Embryo/

[hbw]

It seems that most of the publications on the virtual Embryo and virtual Liver deals with the effect of toxins on the different processes and pathways.

[Mary]

I am still watching the conference so I haven't had time to look around. But I would have expected they'd need a "normal" to compare to changed conditions. Alas.

Answer 2

[Pierre Lindenbaum]

for a database of cell types, you can have a look at the cell line ontology: http://bioportal.bioontology.org/ontologies/1314 and the cell type ontology http://bioportal.bioontology.org/ontologies/1006

[hbw]

The cell type ontology helps, now if there only was data about division and differentiation rates for these cell types. Is no one doing old-style mathematical biology at the cellular level anymore?

Answer 3

[PoGibas]

You should check out this one: http://genome.ucsc.edu/ENCODE/cellTypes.html
All the cell types and protocols used in ENCODE