Literature: Introduction To Ngs Data Analysis?

Question

[Faisal]

I am looking for the text about introduction to NGS data analysis and its challenges. Is there any suitable literature (book or review article) on statistical challenges for analyzying NGS data?

Answer 1

[Sukhi Singh]

Check the tutorial section for a head start.

Few posts:

• Challenges and Solutions in the Analysis of Next Generation Sequence Data
• Tutorial: Workshop - Analysis of Next Generation Sequencing Data
• Tutorial: High Throughput Sequence Analysis with R and Bioconductor
• Tutorial: Introduction to NGS Bioinformatics by the Bioinformatics Team at the University of Texas
• Open wikiBook Next Generation Sequencing (NGS)

[Faisal]

Is there any book about it?

[Damian Kao]

The field is moving too fast for any book to be relevant for too long. The best you can do is maybe check books on microarray analysis.

[Sukhi Singh]

I added one book, can't suggest a specific book. Check few hints here

[Neilfws]

You need to read papers, not books. Are you able to search PubMed effectively?

[Faisal]

yes, actually my focus is on computational challanges in the field of NGS data analysis. Still searching for good latest review on this objective.

Answer 2

[Jonathanjacobs]

There's also an excellent seminar series on iTunesU that covers a wide range of NGS topics - very appropriate for NGS newbies, grad students, etc. - sponsored by the Smithsonian Institution

Smithsonian Institution National Museum of Natural History - Next Gen Sequencing https://itunes.apple.com/us/itunes-u/next-gen-sequencing/id419187633?mt=10

There's also George Church's lectures on NGS and genomics at the MIT Open University https://itunes.apple.com/us/itunes-u/genomics-computational-biology/id341598226?mt=10

Answer 3

[samsara]

My be this not what you are looking for, but this might be helpful http://www.csc.fi/english/csc/courses/archive/ngs_workshop