Forum:Looking For These Previous Posts

Question

[indranipoddar]

Hi,

I am looking for these previous posts on Biostar, but couldn't find them,

• http://www.biostars.org/questions/3498/investigating-snps-of-unknown-significance-uv/3501#3501
• http://www.biostars.org/questions/5259/synonymous-snps-not-so-synonymous-at-all/5262#5262

Mainly I am interested to know what are the tools /ways I can annotate a SNP in intron to see whether the SNP has some functional implication on host gene function etc.. Please share your thoughts.

Thanks,
Indrani

Answer 1

[Istvan Albert]

The links are incorrect, you have extra numbers at the end, they should be:

• http://www.biostars.org/questions/3498/investigating-snps-of-unknown-significance-uv/
• http://www.biostars.org/questions/5259/synonymous-snps-not-so-synonymous-at-all/

[Istvan Albert]

I have considered allowing the longer but incorrect forms to go through unfortunately that is a slippery slope because then it may allow other badly formed urls and only confuses the search engines that do not know anymore which one is the correct url

Answer 2

[Obi Griffith]

It looks like your missing posts are here Investigating Snps Of Unknown Significance (Uv) and here Synonymous Snps Not So Synonymous At All FYI - you could find these just by searching for the titles of the old posts in case this happens to you again.

Lately I have been testing out Ingenuity Variant Analysis which seems to be doing a good job of prioritizing variants in non-coding regions if you choose the right filters. But, not sure if you (or we) can afford to use this system outside of a context of the free trial period or promotional pilot programs. I think their pricing model is still TBD.

[indranipoddar]

Thank you all for all your reply. I will go through these posts. Indrani