Psmc Parameters To Use
1
1
Entering edit mode
11.8 years ago
Gabriel R. ★ 2.9k

I am trying to see how the effective population changes over time for a species. The generation time is about 4 and they live about 15 years. Plus they have a different mutation rate. What parameters should I change from default ? I read the documentation on github but I am still unsure.

genetics • 7.1k views
ADD COMMENT
1
Entering edit mode
11.8 years ago
lh3 33k

The output of the binary psmc is in the so called 2N scale, which is irrelevant to the mutation rate and generation time. You do not need to worry about the two parameters when you run the binary - in fact, you will find that no psmc options are related to those. Mutation rate and generation time affect plotting the real scale. You only need to change the two parameters when plotting using psmc_plot.pl.

ADD COMMENT
0
Entering edit mode

Thanks ! I am just wondering why the example on the website ( -p "4+252+4+6" ) differs from the default parameters (4+53+4).

ADD REPLY
0
Entering edit mode

Sorry. I was not clear. You can change -p and other parameters, but you will note that there are no parameters related to generation time and mutation rate. I have modified my answer accordingly.

ADD REPLY
0
Entering edit mode

I am sorry if I just interrupting the topic discussed above.

Can I know how to scale down Y axis (effective population size)?

The scale generated on my PSMC plot is too big and the changes in effective population size across time was unable to estimate.

ADD REPLY
0
Entering edit mode

You can modify scale using -Y parameter in plotting script from psmc/utils

ADD REPLY

Login before adding your answer.

Traffic: 2729 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6