Do Probesets Correspond To A Genelist In The David Functional Annotation Tool?
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11.8 years ago
mtyler.jason ▴ 120

I am trying to use the DAVID tool to do some gene analysis. I have some probe set intensities for some cancer cell lines. I found this link in the DAVID tool http://david.abcc.ncifcrf.gov/tools.jsp I am a bit confused with the terminology introduced here. It says gene list for the probe sets why is it so? I mean in the example you can see the probe sets like

1007_s_at
1053_at
117_at
121_at
1255_g_at
1294_at
1316_at
1320_at
1405_i_at
1431_at
1438_at
1487_at
1494_f_at
1598_g_at

But why are they called gene list not probe sets. Why?

gene-expression probeset • 2.8k views
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Entering edit mode
11.8 years ago

in general don't get hung up on terminology - the vocabulary is (unfortunately) a bit flexible and people routinely describe related concepts with the same terms.

It is suboptimal but it is the reality. You always have to be defensive and double check results and behaviors.

In this case multiple probes may match the same gene but the tool seems to offer the functionality to sort that out for you and will collapse the probes into genes.

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@Irsan. Thanks got it

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