Tools Of Estimating Linkage Disequilibrium/Recombination Rate And Rr Hotspot Based On Ngs Population Data

Question

[Jianfengmao]

I would like to hear your advice on/recommendation of a tools of estimating Linkage Disequilibrium/Recombination Rate and RR hot-spot based on NGS population data.

For me, I have gotten known with LDhat. But, I have implemented in my study. I wonder if there are robust but more easy-for-use tools like LDhat. Also, I would like to hear your experience of using those ones or good guides for them.

Thanks in advance.

Answer 1

[2184687-1231-83-]

Shameless plug, if you have haplotyped data in the hapmap genotype format, you could try http://www.ub.edu/softevol/variscan