Antibiotics Pdb Models

Question

[Raygozak]

Hi, I'm looking for a place where i can find pdb models for antibiotics. A quick google search didn't show anything so i hope someone knows about it.

Thanks

[Pierre Lindenbaum]

searching for "Ampicillin" in pubchem and pdb returns some hits....

[Raygozak]

thanks i didn't know about pubchem.

[cdsouthan]

Did you want the antibiotic strucuture alone - or complexed with a protein ?

Answer 1

[Neilfws]

1. Go to PDB advanced search.
2. Choose "Biologically Interesting Molecules (from BIRD)" as the query type and "Antibiotic" as the class.
3. Then click "Result Count".

There are currently 143 entries.

Answer 2

[andreas.prlic]

Try this link:

http://www.pdb.org/pdb/search/smartSubquery.do?smartSearchSubtype=BirdQuery&birdClass=Antibiotic

[Neilfws]

That's what I said :)

[andreas.prlic]

true, but it is quicker ;-)

Answer 3

[cdsouthan]

Querying PubChem with "antibiotic" retrieves 1359 CIDs. Of these, 77 have PDB entries

http://www.ncbi.nlm.nih.gov/pccompound?db=pccompound&cmd=search&term=antibiotic%20AND%20%28pccompound_structure[filt]%29&loc=s_frm