Tool To Differentiate Whole Genome And Segmental Duplication

Question

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I was curious whether there is any computational method to differentiate whole genome and segmental duplication?

[Sean Davis]

Could you clarify your question a bit?

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Hi Sean! Actually there are 4 different way by which gene can be duplicated - transposition, tandem, segmental and whole genome duplication. so I was interested to know if we can differentiate whether a gene was duplicated through segmental or whole genome duplication.

[Sean Davis]

So, what data are you analyzing? Do you have WGS data? Or is your question more general?

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Actually it's easy to differentiate tandem and WGD/segmental duplication because of the location of of duplicated genes but i don't know the way to differentiate whether two genes are product of WGD or segmental?

[Biomonika (Noolean)]

Well it would depend on the study of other genes, wouldn't it? If it's segmental duplication, that just the couple of genes are going to be duplicated.