Rosetta - How To Work

Question

[Priya]

Hi

Can anyone tell me how to download and work with rosetta?

priya

[Michael]

This question is to general, what's your specific problem? Otherwise, read the documentation.

[Neilfws]

There is lots of clear, general documentation on their website. If you can't figure out how to download something from a web page, you should probably not be working with Rosetta.

Answer 1

[Zigeuner]

Yeah, it's not the easiest software to get going with. If you have a linux or apple computer, you can download it and install fairly easily. You'll also need the scons package. Here's the compile command to use in the rosetta_source directory:

scons -j 2 bin mode=release (-j 2 uses two CPU's to compile, still takes a while)

that will make a bunch of executables in rosetta_source/bin which can be used for various applications.

The manual is ok: http://www.rosettacommons.org/manual_guide but expects lots of stuff not to work and not make any sense. Remember that it was written by graduate students who want to get their research done, and not necessarily provide software to others.

in the download package there are also a set of demos in the package: rosetta3.2.1_demos.tgz

There's also an associated company: http://www.rosettacommons.org/software/ which does training and consulting work using the software. Nice guys.

good luck

Answer 2

[Michael]

check the homepage?? http://www.rosettacommons.org/software/

Or do you mean rosetta@home? check http://boinc.bakerlab.org/rosetta/ and http://boinc.berkeley.edu/download Took me about 10 sec to google this out.

Answer 3

[Jan Kosinski]

You can try with PyRosetta - a very convenient, easy to install Python interface to Rosetta

http://www.pyrosetta.org/

I would suggest try with PyRosetta first, and only if it is insufficient for your needs, go for regular Rosetta.