Reconstruction Hierarchical Model Of Transcription Factor From Mirna Microarray Expression Data ?

Question

[khan]

Hi

Does anybody know some tools or methods for identifying transcription factor of miRNA and reconstruction of reconstruction hierarchical model of transcription factor ?

Answer 1

[Sasha Fokin]

Hi, Azim!

What do you mean by "hierarchical model of transcription factor"?

That is, network of interactions? If so, then:

we are now building a database and online dataviz tool on cytoscape web -- MirOB (MicroRNA OncoBase).

Database includes validated microRNAs and Transcription Factors Targets associated with human cancers. Currently, MirOB supports only homo sapiens organism.

Network shows all interactions containing transcription factor of miRNA.

You can try our simple tool here.

If the information is open, could you give us a list of genes and miRNA of interest to you. We would like to test our tools.