Would Anyone Share The Metabric Breast Cancer Data With Me Please?

Question

[koukougogo]

Hi folks, I'm working on breast cancer subtype identification and I'm dying for the METABRIC breast cancer data. I've contacted the deposit site, the DATA whatever committee, the corresponding authors, no one has replied to me yet. I have to admit that although it's a Nature paper and the data has been used for DREAM7 challenge, it's almost impossible to get the data... I'm just wondering if anyone would be willing to share the data with me，or any clues where I can download the data? I need the gene expression data and the clinical information. Big thanks!!

Answer 1

[Sean Davis]

These data involve human subjects and potentially identifying information, so it would be highly unethical to share the protected parts of them. As far as I know, you will need to go through the process of requesting access through the Data Access Committee for protected data--there is no way around that.

The data and access details are available through here (at least):

• https://www.ebi.ac.uk/ega/studies/EGAS00000000054
• https://www.ebi.ac.uk/ega/studies/EGAS00000000098
• https://www.ebi.ac.uk/ega/studies/EGAS00000000083

[koukougogo]

Thanks for answering! I've contact EBI but nobody replied to me :( I guess I have to wait

[Hamish]

See EGA: Data Access for an overview of the procedure to follow to request access to the EGA data. Please note that this requires that you contact the appropriate Data Access Committees (DACs) directly for the data sets you want to get access to. Once the DACs have approved access the European Genome-phenome Archive (EGA) folks will contact you with details of how to access the data.

[Charles Warden]

Yes - I agree. For example, DREAM7 participants had to sign a release form saying that the data wouldn't be shared with anybody else or used for any purpose beyond the competition (without additional permission for the data owners)

Answer 2

[satarupabando]

You can download it from CBIOPORTAL. LINK http://www.cbioportal.org/datasets

[johnsonnathant]

Only the clinical data is publically available for METABRIC, which is available from cBIOPORTAL as previously mentioned. The genomic or expression data is only available through the Data Access Committee request.