How To Convert Enzyme Id Of Kegg To Ncbi Protein Id'S

Question

[always_learning]

Hi,

I have few Kegg Enzyme and I want to get the Amino acids sequences for these from NCBI. Any way to get it done ? I can write the scripts but getting way to do it !! I have gon through with Biomart but seems, its not supporting KEGG and KEGG api also seems to not working in this case, Can some one suggest on this.

Thanks Syed

[Neilfws]

Can you be more specific than "KEGG api also seems to not working." What did you try? What was the error or problem? Also, what enzyme IDs do you have - give an example. Be aware that an ID such as 1.1.1.1 maps to multiple genes (and so proteins) from multiple species.

[always_learning]

Sorry for not replying here !! I solved this issue but writing my own scripts for this as I downloaded the Enzyme.dat from ebi and then mapped it with Pro-site id and hence extract in. Kegg api is not supporting any such functionality actually . Thanks for support. Syed

[Neilfws]

Feel free to add the details as a new answer; answering your own questions is fine! (and helpful for others)

Answer 1

[Sam]

Not long ago I stumble upon this website: http://biodbnet.abcc.ncifcrf.gov/, you can easily get the ncbi id from the kegg id.

Another trick is, if you have the hsa id for the gene of interest e.g. TP53: hsa7157, then the corresponding NCBI gene id will be 7157. So you can always try that