Finding New Cancer Biomarket/Drug Target From Ngs Analysis

Question

[Pappu]

I am interesting in finding out novel biomarker/drug target for cancer i.e. liver cancer by combining the analysing of available NGS data (cancer genomes, 1000 genomes projects, COSMIC, RNA-Seq, Chip-Seq etc), Microarray etc dataset. Could you give me some advice to get started?

[David Westergaard]

That's more or less what everyone is trying to do, and the degree of success has been a bit limited. I think http://www.nature.com/nature/journal/v470/n7333/full/nature09792.html is a good article to get started on some of the challenges.

Answer 1

[Charles Warden]

I think you seem to already have a feel for public data. Not sure what else I can say.

This database was published recently:

http://dgidb.genome.wustl.edu/