Question

Poisson Modelling For Snp

0

Entering edit mode

11.0 years ago

sandhya0888 • 0

I have a list of SNPs .How should i do a poisson model for it?

snp • 2.9k views

ADD COMMENT • link updated 11.0 years ago by amcrisan ▴ 370 • written 11.0 years ago by sandhya0888 • 0

1

Entering edit mode

Please provide more detail of what you want to achieve.

ADD REPLY • link 11.0 years ago by Neilfws 49k

0

Entering edit mode

I need to find p-value for each SNP assuming a poisson distribution.I need to know how to calculate the mean value of SNP for each gene.

ADD REPLY • link 11.0 years ago by sandhya0888 • 0

1

Entering edit mode

This is not much more detail...

ADD REPLY • link 11.0 years ago by matted 7.8k

0

Entering edit mode

No, it isn't. "Mean value of SNP for each gene" - what values are being measured? "p-value for each SNP" - what exactly are you comparing and expecting to be different? "Assuming a poisson distribution" - of what?

ADD REPLY • link 11.0 years ago by Neilfws 49k

0

Entering edit mode

R Data Analysis Examples: Poisson Regression

ADD REPLY • link 11.0 years ago by zx8754 12k

score 1 · Answer 1 · 2013-12-06

1

Entering edit mode

11.0 years ago

amcrisan ▴ 370

I wouldn't use a poisson distribution. It's more correct to use the binomial distribution and use each SNP independently.

ADD COMMENT • link 11.0 years ago by amcrisan ▴ 370