The Most Recent Tools To Extracts Population Genetics Parameters

Question

[hosseinv]

Dear friends,

I have a haploid (cp) DNA data file for over 100 individuals (each having 160 kbp) from different populations in fasta format. I was wondering if you could give me any suggestion regarding novel population genetics tools/softwares which are recently used for analyzing these sorts of datasets.

Regards
Hossein

Answer 1

[Giovanni M Dall'Olio]

The answer depends on what you want to do, and on whether you are more a programmer or a computer user. I think that a good software to start is MEGA, which allows to do sequence alignments, calculate phylognetic trees, and some tests for neutrality/selection.

Answer 2

[hosseinv]

Thanks Giovanni,

I also found a very nice review paper at NATURE REVIEW | GENETICS,. So It tells many things too.

Here is the paper:

EXCOFFIER, L., and G. HECKEL, 2006 Computer programs for population genetics data analysis: a survival guide. Nature Reviews Genetics 7: 745-758.

Cheers

Hossein