Help On Getting Data From Tcga

Question

[jack]

Hi all,

I'm trying to get data for mRNA-miRNA expression RNA-seq data (both measured in one sample) from TCGA , but when I download and read it, there are some problems:

1) for one sample there is lot's of txt file on it

2) it's not really clear what is the expression value(should I take raw count or ..)

3) is there any tool to put all the expression value of the genes and sample in one matrix?

[Neilfws]

Regarding point (2): welcome to the world of publicly-available expression data :)

[Jimbou]

Did you tried the browser download? https://genome-cancer.soe.ucsc.edu/proj/site/hgHeatmap/

Answer 1

[lsp03yjh]

You can use starBase Pan-Cancer Analysis Platform . starBase Pan-Cancer Analysis Platform is designed for deciphering Pan-Cancer Networks of lncRNAs, miRNAs, ceRNAs and RNA-binding proteins (RBPs) by mining clinical and expression profiles of 14 cancer types (>6000 samples) from The Cancer Genome Atlas (TCGA) Data Portal (all data available without limitations).

starBase generated Pan-Cancer networks of CLIP-Seq experimentally supported miRNA-lncRNA and miRNA-mRNA interactions.

Pan-Cancer miRNA-mRNA interactions can be available at http://starbase.sysu.edu.cn/targetSite.php