Up To Date Allele Frequency Data - Larger Datasets?

Question

[Devonj]

We are currently using 1000 genomes phase 1 and NHLBI Exome Sequencing Project data ( http://evs.gs.washington.edu/EVS/ ) data to determine variant allele frequency. Both of these are getting relatively old (in genomics terms)

I'm wondering if there are any larger datasets out there yet?

Answer 1

[xb]

How about these?

The larger or most recently updated one goes first !

• STR Allele Frequencies
• The Allele Frequency Net Database
• The ALlele FREquency Database
• HapMap Allele & genotype frequencies

[Devonj]

Thanks for the links but these are relatively unsatisfying. Was hoping for NGS based exome or whole genome data - perhaps I should have specified.

[xb]

Then you can easily compute such values directly from currently available NGS data, e.g. COSMIC, TCGA, etc.