Entering edit mode
11.2 years ago
Adrian Pelin
★
2.7k
If all I have is NGS and a few isolates, is there any way to calculate recombination rate? Based on allele frequencies?
Have you tried LDHAT?
I know it is able to do it, I am however interested in the theory behind it. What does r^2 actually mean? I know it's association of different genotype frequencies, but what does it mean when it is very high or very low in terms of recombination?