Entering edit mode
3.7 years ago
truebeliever24
▴
50
Hi everyone,
I am using the program SMC++ to analyze the demographic history of my dataset. However, I'm having trouble creating bootstrap replicates. There isn't an option in the program, and my understanding is that I want to break up larger scaffolds into smaller segments and then sample with replacement until a resampled genome is produced of equivalent length to the initial genome. My question is, how do I accomplish this? I'm not really seeing a clear path to doing this. My closest guess is using the bootstrapped multihetsep files generated by msmc2, but these are text files, so I'm not sure how they would be read into SMC++. Any help is appreciated!
Thank you.
