Existing Glycomics/Glycan databases with sugar modifications?

Question

[Joe]

Does anyone know if there is a glycomics database with info on sugar modifications etc of proteins?

I have a few protein/gene names and would just like to get some indication of whether they're known to be glycated and whether the sugars have been identified.

Answer 1

[Joe]

Answering my own question (but not in a remotely exhaustive or even particularly thorough manner 😅):

• https://unicarb-db.expasy.org/
• https://acgg.asia/db/gpdb/

[ellimilial]

As a reference for future search - a list from BiOkeanos - https://biokeanos.com/search?q=glycosylation+glycan&sortName=match&sortOrder=asc (adds to the ones you found).

Answer 2

[Giovanni M Dall'Olio]

I believe there are not many large-scale studies on Glycosylation.

Uniprot contains information on Glycosylation, although I think this is based mostly on computational prediction. See this page for more info: https://www.uniprot.org/help/carbohyd

KEGG has the GLYCAN database for glycan structures: https://www.genome.jp/kegg/glycan/ . I think the FTP data contains some annotation between genes and glycans, but I can't access it right now.

[Joe]

It's certainly a chronically understudied and poorly understood topic. Hopefully this thread will be full of ideas in a few more years ;)