Batch Effects in Multiplexed Perturbations
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3.5 years ago
fouerghi20 ▴ 80

I have multiplexed 8 different perturbations on one sample together and as I am demultiplexing and assigning cells to their condition of origin, I am realizing that there are some clusters that appear to be perturbation-specific. I was wondering if there are potential batch effects and if people would recommend doing batch correction prior to clustering the perturbations together.

demultiplexing cellhashing singlecell scRNAseq • 476 views
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