the plot of drug-gene expression correlation

0

Entering edit mode

3.5 years ago

Binghong ▴ 20

does anyone know how to make a plot(drug-gene expression correlation) like this ,thanks the plot of drug-gene expression correlation

correlation drug-gene expression • 1.6k views

ADD COMMENT • link 3.5 years ago by Binghong ▴ 20

0

Entering edit mode

Need little more information. Maybe some reference or a little more explanation on the data type. Like what sort of data do you have for drugs and all.

ADD REPLY • link 3.5 years ago by Nitin Narwade ★ 1.6k

0

Entering edit mode

the plot is from https://pubmed.ncbi.nlm.nih.gov/29894693/ I want to replicate it ,the data are gene expression and PARPi IC50,maybe, but don't know use which tool(pacakage)

ADD REPLY • link 3.5 years ago by Binghong ▴ 20

1

Entering edit mode

Then this is not very hard.

You can use programming (Python: scipy.stats/R: cor function) to calculate the correlation between all the genes and PARPi IC50 values in your experiment. Sort the genes based on obtained correlation and plot them using plotting libraries (Python: matplotlib/R: ggplot2)