what is the best tool to remove PCR duplicates from miRNA seq without UMI?

Question

[Hyper_Odin]

I am not sure about the tools that can process PCR duplicates in miRNA-Seq data. Most of the posts I have read were related to UMI.

I am also not sure if we need to remove the duplicates. Since I was following the deduplication step with UMI indexed samples, i was wondering if we need to do the same without UMI.

Thanks for the help

[Arsenal]

Your post is very similar to this one