The Rademakers team (Genetics of Frontotemporal Dementia) at the VIB-UAntwerp Center for Molecular Neurology, Belgium is seeking a highly motivated PhD student to work on the genetic cause of a rare form of frontotemporal dementia using bioinformatic analysis of multiple omics data types.
In this bioinformatics project, the candidate will investigate the intriguing subtype of frontotemporal dementia with FUS pathology starting from the largest collection of patients with FUS pathology with multiple types of omics data. These datasets include state-of-the-art long-read nanopore DNA and cDNA sequencing for short and structural variants, cytosine methylation, chromatin accessibility, and alternative transcript expression, as well as short-read genome sequencing, deep exome sequencing, RRBS, and RNA-seq, further supplemented by single-cell transcriptomics.
More information can be found here.
