How to perform differential expression on proteomics data?

Question

[lenC_biotecLover]

Hi everyone, I have a proteomic matrix with z-normalized TMT data: row proteins - columns patients. I want to perform a differential expression analysis using R. Does anyone know how can I do this since these are not gene expression data? Thank you

[ATpoint]

Do you have the intensity values available? If so you can use something like DEqMS or DEP from Bioconductor.

[lenC_biotecLover]

No I only have these data