are there GO families?

Question

[fyfes]

Hi, I am wondering if Gene ontology has the same structure as KEGG or EC numbers. I am especially interested whether proteins that were assigned 0004817, 0004814 and 0004818 GO terms have similar function (some kind of 0004800 superfamily, more general function)? thank you for the answer

Answer 1

[Martombo]

if you go on Amigo and select "Inferred tree view", you can see the structure for the GO term. In your case a more general GO term is GO:0004812.

[Alexander]

@Martombo Is there a way to see general GO tree of groups - not specific to particular GO term ? I have heard that there is kind of directed graph of - the most high level GO-groups - then each splits to subgroups - and so on... I wonder where can I find such GO-graph of groups/caterogies ? Thanks in advance !

[Martombo]

Here you can find an overview of the overall structure of GeneOntology. It cannot be described as a simple tree, it's not a strictly hierarchical graph. For this reason, it would be very difficult to have a general representation of the ontology. Or at least I don't know an easy way to have that.