Question

Analyzing TCRseq Data

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Entering edit mode

3.7 years ago

fouerghi20 ▴ 80

Hi everyone,

I am new to TCRseq and I have some data that I would like to start analyzing. I was hoping I can get people's input on what the best package to analyze the 10x V(D)J output would be. I am currently debating between immunarch and scRepertoire, but I do not know enough about TCRseq analysis to know which one would be best to use. Any guidance would be appreciated.

tcr TCRseq scRepetoire Immunarch • 1.1k views

ADD COMMENT • link updated 3.3 years ago by theHumanBorch ▴ 240 • written 3.7 years ago by fouerghi20 ▴ 80

score 1 · Answer 1 · 2021-08-09

Sorry for not seeing this before - I think if you are interested in in-depth repertoire analysis - immunarch is the way to go! If you're TCR-seq is associated with single-cell RNA data, I would [humbly] suggest scRepertoire. If you decide to use the latter, feel free to reach out if you have questions or issues.