'Can\'t connect to eutils.ncbi.nlm.nih.gov:443'

Question

[Akbar]

Using an AWS AMI to predict small RNA targets. Getting following error.

=========Prepping RefSeq Files====================
[Wed Sep  8 08:34:12 UTC 2021]

500 Can't connect to eutils.ncbi.nlm.nih.gov:443
No do_post output returned from 'https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=nucleotide&id=NZ_CP039025&rettype=native&retmode=text&edirect=6.00&tool=edirect&email=[e-mail]'
Result of do_post http request is
$VAR1 = bless( {
                 '_msg' => 'Can\'t connect to eutils.ncbi.nlm.nih.gov:443',
                 '_request' => bless( {
                                        '_headers' => bless( {
                                                               'user-agent' => 'libwww-perl/6.15',
                                                               'content-type' => 'application/x-www-form-urlencoded'
                                                             }, 'HTTP::Headers' ),
                                        '_method' => 'POST',
                                        '_uri' => bless( do{\(my $o = 'https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi')}, 'URI::https' ),
                                        '_content' => 'db=nucleotide&id=NZ_CP039025&rettype=native&retmode=text&edirect=6.00&tool=edirect&email=[e-mail]'
                                      }, 'HTTP::Request' ),
                 '_headers' => bless( {
                                        '::std_case' => {
                                                          'client-date' => 'Client-Date',
                                                          'client-warning' => 'Client-Warning'
                                                        },
                                        'client-warning' => 'Internal response',
                                        'client-date' => 'Wed, 08 Sep 2021 08:34:12 GMT',
                                        'content-type' => 'text/plain'
                                      }, 'HTTP::Headers' ),
                 '_rc' => 500,
                 '_content' => 'Can\'t connect to eutils.ncbi.nlm.nih.gov:443

SSL connect attempt failed error:14077410:SSL routines:SSL23_GET_SERVER_HELLO:sslv3 alert handshake failure at /usr/share/perl5/LWP/Protocol/http.pm line 47.
'
               }, 'HTTP::Response' );

Cannot retrieve BioProject or BioSample ID for accession NZ_CP039025 at /software/IntaRNA1.0.4/get_refseq_from_ftp.pl line 16.
Cannot open NZ_CP039025.gb

Thanks in advance