gatk legacy bundles (where to get Mills_and_1000G_gold_standard.indels.hg19.sites.vcf.gz)
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3.5 years ago
nkinney06 ▴ 140

I need the known indels vcf to run gatk BaseRecalibrator. So I need hg19 (not the b37) version of the known indels: Mills_and_1000G_gold_standard.indels.hg19.sites.vcf.gz

However this file is no longer available at: ftp://gsapubftp-anonymous@ftp.broadinstitute.org/bundle/hg19/Mills_and_1000G_gold_standard.indels.hg19.sites.vcf.gz

the broad institute documentation says the ftp site was disabled last year (https://gatk.broadinstitute.org/hc/en-us/articles/360035890811) so I checked the gcp bucket using the following command: gsutil ls gs://gatk-legacy-bundles/hg19/

output:

gs://gatk-legacy-bundles/hg19/
gs://gatk-legacy-bundles/hg19/ucsc.hg19.dict
gs://gatk-legacy-bundles/hg19/ucsc.hg19.fasta
gs://gatk-legacy-bundles/hg19/ucsc.hg19.fasta.fai

In other words, I cant find Mills_and_1000G_gold_standard.indels.hg19.sites.vcf.gz in the gatk-legacy-bundles bucket. Does anyone know where this file is now available for download?

indels gatk • 5.9k views
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The files are available in this bucket.

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Thanks but those are all hg38 not hg19. I know about liftover tools but the file I need should still be available

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Your best bet may be to ask GATK support. hg19 version does not seem to be readily available via a search.

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These files are for hg38, not hg19. Do you know were are the files for hg19 ?

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Please ask GATK support via their forum and then come back to provide that information here for future visitors.

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8
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2.6 years ago
ning ▴ 120

You can find the legacy bundle at their ftp site, but you have to be logged in as gsapubftp-anonymous (logging in as anonymous will not show the bundle).

ShujiaHuang on GitHub provides some wget commands to retrieve those files:

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thanks soooooo much

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