Volcano 3D plot on single cell seurat data ?

Question

[Ondina]

I'm currently searching for a way of using volcano3D on single cell data analyzed with Seurat. Volcano3D looks like a fun and interesting method for DE analysis representation but I don't know which is the right way to do it from a single cell seurat object? EnhancedVolcano works like a charm with DE analysis by Seurat and I wanted to know if there is a similar way to get volcano3d working with this kind of data.

This is how Volcano3D works:

1st tutorial

Tutorial on their website

[Giovanni M Dall'Olio]

What would the 3rd dimension be, after log(pvalue) and log(odds)?

Answer 1

[Ondina]

Currently searching for a solution on this Volcano3D's issue, it's working more or less thanks to Katriona Goldmann, one of the Volcano3D developpers, I'll make some few adjustements:

Volcano 3D github issues section